Vigabatrin dosing during haemodialysis

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Vigabatrin dosing during haemodialysis

The antiepileptic drug vigabatrin has shown efficacy in the treatment of patients with refractory epilepsy. Unlike many other antiepileptics it is not bound to plasma protein and mainly eliminated by the kidney. Although the therapeutic and toxic serum concentration range is not clearly defined and efficacy and toxicity are not closely correlated with the dose, factors decreasing vigabatrin eli...

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ژورنال

عنوان ژورنال: Seizure

سال: 1996

ISSN: 1059-1311

DOI: 10.1016/s1059-1311(96)80043-4